The C-130 left
It was the first American relief flight to the region, where thousands are feared dead and tens of thousands more homeless as a result of Friday's typhoon.
The flight was headed for Tacloban, a city badly hit by the storm and in desperate need of assistance.
Photo courtesy of Getty Images
Military spokesman Lt. Jim Alagao said that 275 others were confirmed missing from the storm, one of the strongest on record.
The death toll is expected to rise considerably. Two provincial officials predicted Sunday that it could reach 10,000 or more.